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Development of Stem Cell Strategies for the Prevention of Age-Related Muscle Loss

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SKU:
827008329595*
Author:
Marni D. Boppart
Published:
2007
Length:
297 minutes
Development of Stem Cell Strategies for the Prevention of Age-Related Muscle Lossdiscusses the latest science in an emerging area of muscle physiology research. Among thetopics covered, the DVD discusses satellite and mesenchymal stem cells attendant tosarcopenia. In addition the DVD reviews the results of numerous studies involving stem cellresearch that examined therapeutic strategies to increase cell proliferation and new fibersynthesis in musculature. Furthermore, the DVD looks at how those factors may contributeto the regeneration of muscle mass and restoration of function, consequently slowing theprogression of disability with age.

Among the topics covered:
  • Aging and satellite cells
  • Systemic factors in young serum rejuvenate aged satellite cells
  • Satellite cell
  • mMSCs in mouse skeletal muscle are Sca-1*CD45
  • The majority of Sca-1*CD45 stem cells in skeletal muscle postexercise are pericytes
  • mMCSs release paracrine factors in response to mechanical strain
  • Development of strategies to combat sarcopenia
  • Extracellular matrix & mMSC function