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The Role of Redox–Sensitive Sirtuins in Exercise and Aging

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SKU:
827008331499*
Author:
Zsolt Radak
Published:
2008
Length:
43 minutes
Studies on aging in model systems have identified a class of proteins, called sirtuins, that help counteract aging. The Role of Redox–Sensitive Sirtuins in Exercise and Aging examines whether these anti-aging genes are impacted by exercise. The DVD also looks at the affect of sirtuins in mitigating aging by regulating mitochondrial function.

Among the topics covered: 

• Sir2 silences muscle differentiation with redox-sensitive manner 
• Do sirtuins interfere with thebiogenesis of mitochondria? 
• Diet-sensitive expression of Sirt3 andAMPK in muscle tissue 
• The levels of low protease and HSP78 
• Posttranslational modifications of skeletalmuscle with aging and exercise 
• Oxidative DNA damage and repair 
• Passive avoidance test 
• Take-home messages